Description
L-carnitine (β-hydroxy-γ-N-trimethylaminobutyric acid) is a small quaternary ammonium compound, not a peptide. It is synthesised in the body from lysine and methionine and is required to move long-chain fatty acids into the mitochondria for beta-oxidation.
What is L-Carnitine?
Long-chain fatty acids cannot cross the inner mitochondrial membrane on their own. Carnitine palmitoyltransferase 1 (CPT1) on the outer membrane converts acyl-CoA to acylcarnitine, the carnitine-acylcarnitine translocase moves it across, and CPT2 regenerates acyl-CoA inside the matrix. Carnitine also buffers the acetyl-CoA pool by forming acetylcarnitine. Primary carnitine deficiency, caused by mutations in the OCTN2 transporter, is the classic human disorder of this system.
Research Applications
- Mitochondrial fatty acid oxidation (CPT1/CPT2 shuttle)
- Acylcarnitine profiling and metabolomics standards
- Acetyl-CoA buffering and metabolic flexibility in cell models
- OCTN2 transporter studies
- Comparison with the combined formulation LC216
Product Specifications
- Compound: L-carnitine, CAS 541-15-1
- Molecular formula: C7H15NO3, molar mass 161.20 g/mol
- Size: as listed in the product options
- Purity: ≥99% (HPLC), manufactured in the USA
- Storage: store sealed at 2-8°C, protected from light
For research use only. Not for human or veterinary use. Not a drug, food, or cosmetic. Sold to qualified researchers for in-vitro and laboratory research.





