Description
N-Acetyl Semax Amidate, also called NA-Semax-Amidate, is a synthetic ACTH(4-10) analog with protecting groups on both ends of its seven-residue chain. This product is the lyophilized powder version, packed in a sealed vial for reconstitution in the laboratory. Chemically it matches the spray listing and differs only in physical form.
What is N-Acetyl Semax Amidate?
The sequence Met-Glu-His-Phe-Pro-Gly-Pro pairs a short ACTH fragment with a stabilizing Pro-Gly-Pro tail. Adding an N-terminal acetyl group and a C-terminal amide yields a molecule that is uncharged at both termini. These changes are studied for their effect on resistance to exopeptidases and on lipophilicity, which matters in experiments on transport across biological barriers.
Dry powder gives researchers control over solvent, pH, and final concentration. It also allows direct comparison with native Semax and with singly acetylated N-Acetyl Semax under matched conditions. Laboratory work with this class of compounds has examined neurotrophic factor expression, gene transcription in brain tissue after induced ischemia, and performance in rodent learning tasks. Weighed portions of dry powder also simplify preparation of calibration standards for HPLC and mass spectrometry methods that track the intact peptide and its fragments.
Research Applications
- Exopeptidase stability of fully capped peptides
- Barrier permeability and lipophilicity experiments
- Neurotrophic factor expression in rodent brain
- Learning and memory tasks in animal models
- Head-to-head comparisons of Semax analogs
Product Specifications
- Available sizes: 20mg, 30mg
- Form: Lyophilized powder in sealed vial
- Sequence: Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH2
- Purity: ≥99% (HPLC)
- Storage: Store lyophilized product at -20°C; protect from light
For research use only. Not for human or veterinary use. Not a drug, food, or cosmetic. Sold to qualified researchers for in-vitro and laboratory research.






