GHK-Cu 2mg (60 Capsules)

Description

GHK-Cu, also known as copper tripeptide-1, is a complex of the tripeptide glycyl-L-histidyl-L-lysine with a copper(II) ion. The peptide was first isolated from human plasma by Loren Pickart in the 1970s. This product supplies GHK-Cu in capsule form, 60 capsules per bottle.

What are GHK-Cu Capsules?

GHK binds copper with high affinity and is thought to act partly as a copper carrier in tissues. Early cell culture work showed that GHK-Cu stimulated synthesis of collagen and glycosaminoglycans by fibroblasts. Later studies examined its effects on metalloproteinase activity and antioxidant enzymes, and gene expression analyses using the Broad Institute’s Connectivity Map linked GHK to changes in the expression of a large number of human genes.

The capsule presentation differs from the lyophilized and spray forms. It suits laboratory work on solid-form materials, such as dissolution testing, stability of the peptide-copper complex in a dry matrix, and behavior in simulated gastric and intestinal fluids. Peptides are generally vulnerable to digestive proteases, which makes this format a research subject in its own right. The short sequence is also easy to characterize by HPLC and mass spectrometry.

Research Applications

• Fibroblast collagen and glycosaminoglycan synthesis in vitro
• Copper binding and transport studies
• Gene expression profiling
• Dissolution and stability testing of solid-form peptide formulations
• Protease susceptibility in simulated gastrointestinal fluids

Product Specifications

• Available options: 50mg, 100mg
• Form: Capsules, 60 per bottle
• Compound: Glycyl-L-histidyl-L-lysine copper(II) complex
• Purity: ≥99% (HPLC)
• Storage: Store in a cool, dry place away from light and moisture

For research use only. Not for human or veterinary use. Not a drug, food, or cosmetic. Sold to qualified researchers for in-vitro and laboratory research.