Price range: $61.99 through $89.99
Selank capped with an N-terminal acetyl group and a C-terminal amide, supplied as a spray solution for research on exopeptidase resistance and comparative peptide stability.
N-Acetyl Selank Amidate Spray contains Selank carrying two terminal modifications: an acetyl group at the N-terminus and an amide in place of the C-terminal carboxylic acid. Selank itself is a seven-residue synthetic peptide built on the tuftsin sequence. This listing supplies the dual-capped compound as a spray solution in 20mg and 30mg sizes.
Both ends of a linear peptide are exposed to exopeptidases. Aminopeptidases trim residues from the N-terminus, while carboxypeptidases work from the C-terminus. Capping both ends is a common strategy for studying whether a sequence lasts longer in plasma, tissue homogenates, or buffer. Amidation also removes the negative charge of the terminal carboxyl group, which can change how the molecule interacts with membranes and receptors.
The parent peptide, Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro), came out of regulatory peptide work at the Russian Academy of Sciences. Published animal studies have measured its effects on anxiety-like behavior, on hippocampal BDNF levels, and on expression of cytokines such as IL-6. The double-modified analog allows side-by-side comparison with both the native peptide and the singly acetylated N-Acetyl Selank.
For research use only. Not for human or veterinary use. Not a drug, food, or cosmetic. Sold to qualified researchers for in-vitro and laboratory research.
| Weight | 20mg, 30mg |
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